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A practical guide on explainable ai techniques applied on biomedical use case applications
Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining detailed explanations of their behaviour. As opaque machine learning models are increasingly being employed to make important predictions in critical environments,…
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Graph-guided random forest for gene set selection
Machine learning methods can detect complex relationships between variables, but usually do not exploit domain knowledge. This is a limitation because in many scientific disciplines, such as systems biology, domain knowledge is available in the form of graphs or networks, and its use can improve model performance. We need network-based algorithms that are versatile and…
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Network module detection from multi-modal node features with a greedy decision forest for actionable explainable AI
Machine learning methods can detect complex relationships between variables, but usually do not exploit domain knowledge. This is a limitation because in many scientific disciplines, such as systems biology, domain knowledge is available in the form of graphs or networks, and its use can improve model performance. We need network-based algorithms that are versatile and…
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Towards multi-modal causability with graph neural networks enabling information fusion for explainable AI
AI is remarkably successful and outperforms human experts in certain tasks, even in complex domains such as medicine. Humans on the other hand are experts at multi-modal thinking and can embed new inputs almost instantly into a conceptual knowledge space shaped by experience. In many fields the aim is to build systems capable of explaining…
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Classification by ordinal sums of conjunctive and disjunctive functions for explainable AI and interpretable machine learning solutions
We propose a novel classification according to aggregation functions of mixed behaviour by variability in ordinal sums of conjunctive and disjunctive functions. Consequently, domain experts are empowered to assign only the most important observations regarding the considered attributes. This has the advantage that the variability of the functions provides opportunities for machine learning to learn…
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The featurecloud ai store for federated learning in biomedicine and beyond
Machine Learning (ML) and Artificial Intelligence (AI) have shown promising results in many areas and are driven by the increasing amount of available data. However, this data is often distributed across different institutions and cannot be shared due to privacy concerns. Privacy-preserving methods, such as Federated Learning (FL), allow for training ML models without sharing…
