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Reviewing the essential roles of remote phenotyping, GWAS and explainable AI in practical marker-assisted selection for drought-tolerant winter wheat breeding
Marker-assisted selection (MAS) plays a crucial role in crop breeding improving the speed and precision of conventional breeding programmes by quickly and reliably identifying and selecting plants with desired traits. However, the efficacy of MAS depends on several prerequisites, with precise phenotyping being a key aspect of any plant breeding programme. Recent advancements in high-throughput…
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CLARUS: an interactive explainable AI platform for manual counterfactuals in graph neural networks
BackgroundLack of trust in artificial intelligence (AI) models in medicine is still the key blockage for the use of AI in clinical decision support systems (CDSS). Although AI models are already performing excellently in systems medicine, their black-box nature entails that patient-specific decisions are incomprehensible for the physician. Explainable AI (XAI) algorithms aim to “explain”…
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Human-in-the-loop reinforcement learning: A survey and position on requirements, challenges, and opportunities
Artificial intelligence (AI) and especially reinforcement learning (RL) have the potential to enable agents to learn and perform tasks autonomously with superhuman performance. However, we consider RL as fundamentally a Human-in-the-Loop (HITL) paradigm, even when an agent eventually performs its task autonomously. View publication
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On generating trustworthy counterfactual explanations
Deep learning models like chatGPT exemplify AI success but necessitate a deeper understanding of trust in critical sectors. Trust can be achieved using counterfactual explanations, which is how humans become familiar with unknown processes; by understanding the hypothetical input circumstances under which the output changes. We argue that the generation of counterfactual explanations requires several…
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Be careful when evaluating explanations regarding ground truth
Evaluating explanations of image classifiers regarding ground truth, e.g. segmentation masks defined by human perception, primarily evaluates the quality of the models under consideration rather than the explanation methods themselves. Driven by this observation, we propose a framework for evaluating the robustness of safety-critical systems that a deep neural network with an explanation method. These…
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Ensemble-GNN: federated ensemble learning with graph neural networks for disease module discovery and classification
Summary Federated learning enables collaboration in medicine, where data is scattered across multiple centers without the need to aggregate the data in a central cloud. While, in general, machine learning models can be applied to a wide range of data types, graph neural networks (GNNs) are particularly developed for graphs, which are very common in…
